A Mathematical Bivariate Generalized Poisson Model for Cortisol Awakening Response with Multiple Sclerosis in Humans

نویسنده

  • S. Lakshmi
چکیده

In this paper, we discuss about the bivariate generalized Poisson distribution for the cortisol awakening response and multiple sclerosis in humans. Dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis has been frequently been reported in multiple sclerosis (MS). So far, HPA axis function in MS has predominantly been studied under pharmacological stimulation which is associated with a series of methodological caveats. Knowledge of circadian cortisol patterns and cortisol awakening response (CAR) is still limited. We have found the probability generating function and moment generating function for cortisol awakening response and the corresponding mathematical figures 3.1 to 3.6 have been given in section 3.

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تاریخ انتشار 2014